Early Tests Find Nanoshell Therapy Effective Against Brain 
Cancer
Rice University bioengineers and physician-scientists at Baylor 
College of Medicine and Texas Children's Hospital have successfully destroyed 
tumors of human brain cancer cells in the first animal tests of a minimally 
invasive treatment that zaps glioma tumors with heat. The tests involved 
nanoshells, light-activated nanoparticles that are designed to destroy tumors 
with heat and avoid the unwanted side effects of drug and radiation therapies. 
The investigators published the results of their study in the Journal of 
Neuro-Oncology.
read more
Trapping nanoshells using Trestles CW - continuum wave tunable Ti:Sapphire laser from Del Mar Photonics
 
Brooke Hester is a PhD student working in the Optical Tweezers Lab at the 
National Institute of Standards and Technology (NIST). In this video she tells 
about trapping polystyrene spheres and nanoshells using Trestles CW - continuum 
wave tunable Ti:Sapphire laser from Del Mar Photonics.
Nanoshells for those experiments were provided by Naomi Halas.
Gold nanoshells were invented in the mid-1990s by Naomi Halas. Dr. Halas is the 
co-principal investigator of the Cancer Nanotechnology Platform Partnership at 
Rice, one of 12 funded by the National Cancer Institute. Nanoshells are like 
tiny malted milk balls that are coated with gold rather than chocolate. Their 
core is non-conducting, and by varying the size of the core and thickness of the 
shell, researchers can tune them to respond to different wavelengths of light. 
Houston-based biomedical firm Nanospectra Biosciences, which holds the license 
for medical use of Rice's nanoshell technology, began the first human clinical 
trial of nanoshell phototherapy in 2008. Dr. West, a co-founder and director of 
Nanospectra Biosciences, said the new glioma study is part of a larger ongoing 
effort within the Texas Medical Center to adapt nanoshell phototherapy for use 
against a variety of cancers.
Trestles brochure (both femtosecond and CW versions)
We also offer Tretsles CW Ti:Saphire laser with build in pump laser with pump power from 3 to 10 Watt.
Trestles CW Opus Specifications (request 
a quote)
Ti:Sapphire CW oscillator
Tuning range, nm: 700-1000*
Output power (free-space), mW: 300 (@800 nm, 3W pump)
Bandwidth: <45 GHz
<20 GHz (with 1 etalon**)
<2 GHz (with 2 etalons**)
Spatial mode: TEMoo
Divergence: <2 mrad
Polarization: horizontal
* - manually controlled birefringent filter for
wavelength tuning is included
** - not included, please see below
Fiber-coupled output: single-mode fiber 700-1300 nm,
4 um, 1 m FC-FC
Output power at fiber output: >10 mW@700-1000 nm
OPUS DPSS PUMP LASER, 3 W OUTPUT
POWER 3 W
WAVELENGTH 532 NM
BEAM SIZE 2.0 MM
SPATIAL MODE TEM00
M SQUARED < 1.1
POWER STABILITY < 0.4 % RMS
NOISE < 0.4% RMS
Accessories 
3BRF-TM Upgrade - Upgrade to motorized 3-plate birefringent filter for USB 
wavelength tuning
Thick (thin) etalon with mount (manual tuning)
Thick (thin) etalon with mount (step motor controlled tuning)
Closed-loop chiller
 
Trestles CW available free free space as well as fiber-coupled output
Fiber-coupled output: single-mode fiber 700-1300 nm, 4 um, 1 m FC-FC
Output power at fiber output: >10 mW@700-1000 nm
Trestles CW Opus continuum wave Ti:Sapphire laser with built in 3 Watt DPSS laser
    
Dimensions of Trestles CW Opus continuum wave Ti:Sapphire laser with built in 3 Watt DPSS laser

The Trestles CW Opus weight is about 20 kg.
 
DPSS pump laser control unit
| Features * RS232 control * large LCD * advanced funtionality * analogue modulation * power failure LED * emission status LED * remote interlock * full switch-mode operation * silent operation * compact, low-profile design 
      | 
    Supply voltage 12V dc frequency dc input Required Clearance * 100 mm at rear Connections mains 12V dc input modulation 9 way D-type RS232 9 way D-type umbilical 25 way D-type Modulation input range 0 - 4 V rise time 10 usec bandwidth 0 - 30 kHz  | 
  
Chiller - weight 11 kg, W 220mm x D 333mm x H 390mm

Del Mar Photonics, Inc.
4119 Twilight Ridge
San Diego, CA 92130
tel: (858) 876-3133
fax: (858) 630-2376
    Skype: delmarphotonics
sales@dmphotonics.com
    www.twitter.com/TiSapphire